Bioprocess Hub
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Tools & forms

Bioprocess calculators and URS document generators for upstream, downstream, lab prep and equipment specification. Search by name, group or tag, then open a form to use it.

Fill any URS yourself β€” free. Complete the form manually and download the document at no cost. Or use our AI assistant to draft it in seconds: it fills the form from a short brief, suggests specs, checks ASME/compliance by location, and can recommend manufacturers.
Upstream Titer & Total Yield
43 uses
Upstream

Estimate total product mass and volumetric productivity from titer, working volume and run time.

titeryieldproductivityfermentationcell culture
Downstream Step Recovery
34 uses
Downstream

Multiply per-step recoveries to see overall yield across a purification train β€” and where you lose the most.

yieldrecoverypurificationchromatographydsp
Dilution (C₁V₁ = Cβ‚‚Vβ‚‚)
34 uses
Lab prep

Work out how much stock and diluent you need to reach a target concentration and volume.

dilutionconcentrationbufferstockc1v1
Fed-Batch Feed Calculator
73 uses
Upstream

Design a fed-batch feeding profile β€” exponential, linear, constant or step-wise bolus β€” with pump schedule, predicted biomass & volume, charts and safety warnings. Includes organism presets.

fed-batchexponential feedlinear feedconstant feedstep-wise bolusfeeding strategyfermentationspecific growth rateE. coliCHO
Process Mode Selector
33 uses
Process design

Answer 6 questions and get a ranked recommendation β€” batch vs fed-batch vs perfusion β€” with the trade-offs for your case.

decision toolbatchfed-batchperfusioncontinuousselectionupstream
Upstream Sizing from Annual Capacity
91 uses
Upstream

Size the bioreactor working volume (and number of reactors) needed to hit an annual production target, from titer, downstream yield and batch cycle time.

bioreactor sizingannual capacityworking volumescale-upbatchesfermenter
OD₆₀₀ β†’ Cell Density
33 uses
Upstream

Convert an optical density reading into an approximate cell concentration for your organism.

od600cell densitygrowthoptical densitybiomass
URS β€” Fermenter / Bioreactor
88 uses
URS

Bioreactor system questionnaire β€” capture full client requirements for a fermenter / bioreactor.

ursfermenterbioreactorupstreamquestionnairegmpπŸ”’ Free account
URS β€” Mixing Vessel
30 uses
URS

Generate a User Requirement Specification for a mixing / preparation vessel.

ursmixing vesselpreparationspecificationgmpπŸ”’ Free account
URS β€” Process Vessel
28 uses
URS

Generate a User Requirement Specification for a process / storage vessel.

ursprocess vesselstoragetankspecificationgmpπŸ”’ Free account
URS β€” TFF Skid
38 uses
URS

Generate a User Requirement Specification for a tangential-flow filtration (TFF) system.

urstfffiltrationdownstreamultrafiltrationspecificationπŸ”’ Free account
URS β€” Centrifuge
38 uses
URS

Generate a User Requirement Specification for a process centrifuge.

urscentrifugeseparationclarificationdownstreamspecificationπŸ”’ Free account